Centenary offers majors in the arts and sciences, as well as numerous academic concentrations, a variety of pre-professional programs, and two graduate programs.
| Major | Minor | Masters | |
| Accounting | M | m | |
| Art | M | m | |
| Art History | m | ||
| Biochemistry | M | ||
| Biology | M | m | |
| Business Administration | M | m | M.B.A |
| Chemistry | M | m | |
| Communication | M | m | |
| Computer Science | m | ||
| Economics | M | m | |
| Education, Elementary | M | m | M.A.T |
| Education, Secondary | M | m | M.A.T |
| Engineering | 3-2 | 3-3 | ||
| English | M | m | |
| Environment and Society | m | ||
| French | M | m | |
| Gender Studies | m | ||
| Geology | M | m | |
| History | M | m | |
| Individualized Major | M | ||
| Kinesiology | M | ||
| Legal Studies | m | ||
| Mathematics | M | m | |
| Music | M | m | |
| Museum Management | m | ||
| Neuroscience | M | m | |
| Philosophy | M | m | |
| Political Science | M | m | |
| Physics | M | m | |
| Psychology | M | m | |
| Religious Studies | m | ||
| Sociology | M | m | |
| Spanish | m | ||
| Sport Management | M | m | |
| Theatre | M | m | |
| Vocal Music Education | M | M.A.T |